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HAT (Hypoxanthine, Aminopterin, Thymidine)

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HAT (Hypoxanthine, Aminopterin, Thymidine)

Catalog # 25-046-CI
Pack Size: 1 x 100 mL
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Technical Advantage:  Lower documented Endotoxin content then offerings from other major suppliers.

HAT Medium (hypoxanthine-aminopterin-thymidine medium) is used in mammalian cell culture for post-fusion selection to eliminate certain types of myeloma cells.  The combination of aminopterin, a drug that acts as a powerful folate metabolism inhibitor, with hyproxanthine and thymidine, which are intermediates in DNA synthesis, provides a form of artificial selection for cells containing functioning hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and thymidine kinase (TK).  These enzymes are involved in DNA synthesis and cell division.  HAT medium is often used in the preparation of monoclonal antibodies.

-  Complete Certificate of Analysis available for each production lot, along with full formulation information

-  Produced under the highest industry standards to ensure superior results